Serum Cover Art

Serum (v0.1.6)

Simulation 14.29 GB v0.1.6 685 views

Game Overview

A poisoned island shrouded in unnatural fog makes survival feel like a race against a ticking clock. Serum is a first-person survival adventure where a life-sustaining injection keeps you alive, but every dose also becomes a gamble with dangerous consequences. Mutated wildlife, ruined facilities, and traces of a lost scientific project give the setting a bleak, tense atmosphere rather than a simple sandbox wilderness feel. The central mystery gradually pushes you beyond basic survival as you search for answers about the serum, the disaster, and a possible escape.

Moment-to-moment play revolves around scavenging materials, gathering biological samples, and returning to shelter before your dwindling supply runs out. Plants and creatures provide ingredients for experimental brews, allowing you to create temporary boosts for mobility, combat, resistance, and other useful abilities; managing their side effects matters as much as discovering powerful recipes. Crafting covers practical tools, defenses, traps, and weapons, while a safe-zone system lets you establish a more reliable source of the precious substance. Combat supports close-range clubs and spears alongside bows and throwable weapons, with upgrades and serum-infused modifications giving you better odds against the island’s increasingly dangerous monsters.

What separates Serum from more familiar crafting survival games is how its survival pressure feeds directly into its progression system. You are not merely collecting food and building a base; every expedition demands preparation, recipe knowledge, stamina management, and a plan for getting home alive. Unreal Engine 5 visuals give its different biomes and decaying research sites a sharp, atmospheric presentation, while the brewing system encourages experimentation instead of locking upgrades behind a straightforward skill tree. Players who enjoy the exploration and crafting of The Forest or Subnautica, but want a harsher timer-driven structure and more active combat, are likely to find plenty to like here.

Screenshots

Installation

  1. Click the green button below to be redirected to UploadHaven.
  2. Wait 15 seconds, then hit “Free Download.” (Free downloads may be slower — upgrade to UploadHaven Pro for faster speeds.)
  3. Once downloaded, right-click the .zip file and choose “Extract to Serum.” (You’ll need 7-Zip for this.)
  4. Open the extracted folder and run the game as administrator.
  5. Enjoy! 🎮 If you see missing DLL errors, check the _Redist folder inside and install what’s needed.

System Requirements

  • Requires a 64-bit processor and operating system
  • OS: Windows 10 (x64)
  • Processor: Intel Core i5-8400 or AMD Ryzen 5 2600X
  • Memory: 12 GB RAM
  • Graphics: NVIDIA GeForce GTX 1070, 8 GB or AMD Radeon RX Vega 56, 8 GB or Intel Arc A750, 8 GB
  • DirectX: Version 11
  • Storage: 15 GB available space
  • Sound Card: DirectX compatible
  • Additional Notes: Low settings, 1080p @ 30 FPS. CPU must support at least the SSE3 instruction set. Does not require the AVX instruction set.
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Setup Guide & Troubleshooting

How do I fix missing DLL errors for Serum (v0.1.6)?

After extracting Serum (v0.1.6), navigate to the _Redist or _CommonRedist folder inside the game directory and install DirectX, Vcredist, and any other dependencies included.

What should I do if the downloaded file is corrupted?

The full archive is 14.29 GB — make sure your download completed fully before extracting. Use 7-Zip to extract the files. If you still see a "file corrupted" error, re-download and try again.

Why should I run the game as administrator?

Right-click the game executable and select "Run as Administrator" to avoid save file issues and permission errors. This is especially important on the first launch.

How do I update my GPU drivers for this game?

Serum (v0.1.6) requires a NVIDIA GeForce GTX 1070, 8 GB or AMD Radeon RX Vega 56, 8 GB or Intel Arc A750, 8 GB or equivalent. Update your NVIDIA or AMD drivers to the latest version for the best performance.

The game won't launch — what should I try?

This game requires Version 11. Try running in compatibility mode, install the latest DirectX runtime, or install the All-in-One VC Redist Package.

My antivirus is blocking the game — is it safe?

Antivirus false positives are common with pre-installed games. Temporarily pause your antivirus during extraction to prevent it from quarantining game files. You can re-enable it after the extraction completes.

Need more help? Browse our FAQ & Troubleshooting Guide for solutions to common issues.
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